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Increased NNMT expression has also been reported in muscle-wasting conditions such as Duchenne Muscular Dystrophy (DMD)

Gerontologist 2016;56(6):11611174

Published research suggests this interaction may be bidirectional, with BPC-157 appearing to promote or counteract NO system effects depending on the experimental context (Sikiric et al., 2014)

This includes: Acknowledging that the 8- or 12-weekly schedule is not suitable for everyone

Excessive cardio can impair muscle retention and may be counterproductive for body composition goals